Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 14/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 13/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 13/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10631305 | 0.91 | CES2 (0.38) | TAS1R3TAS1R1TAS1R2CES2CES1 | |
| SCHEMBL6740803 | 0.86 | TAS1R3 (0.45) | TAS1R3TAS1R1TAS1R2CES2CES1 | |
| SCHEMBL9019887 | 0.83 | CES2 (0.40) | TAS1R3TAS1R1TAS1R2CES2CES1 | |
| SCHEMBL7652879 | 0.82 | TAS1R3 (0.42) | TAS1R3TAS1R1TAS1R2CES2CES1 | |
| SCHEMBL28071165 | 0.81 | CES2 (0.52) | CES2CES1ALDH1A1 | |
| SCHEMBL2777861 | 0.79 | TAS1R3 (0.39) | TAS1R3TAS1R1TAS1R2CES2CES1 | |
| SCHEMBL8102971 | 0.78 | CES2 (0.35) | TAS1R3TAS1R1TAS1R2CES2CES1 | |
| SCHEMBL19478297 | 0.78 | TSHR (0.42) | TAS1R3TAS1R1TAS1R2CES2CES1 | |
| SCHEMBL9134506 | 0.77 | CES2 (0.41) | CES2CES1ALDH1A1 | |
| SCHEMBL9418220 | 0.75 | CES2 (0.50) | CES2CES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418175-B1 | Isoxazoles herbicides | RHONE POULENC AGRICULTURE (GB) | 1996-07-17 | — | — | EP | disclosed |
| EP-0418175-A2 | Isoxazoles herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1991-03-20 | — | — | EP | disclosed |