Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.53 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL370477 | 0.98 | BAZ2B (0.54) | BAZ2BBAZ2AALDH1A1CYP1A2GAA | |
| SCHEMBL17992239 | 0.78 | GABRP (0.49) | BAZ2BBAZ2AALDH1A1CYP1A2GAA | |
| SCHEMBL8103043 | 0.77 | BAZ2B (0.53) | BAZ2BBAZ2AALDH1A1CYP1A2GAA | |
| SCHEMBL162449 | 0.76 | BAZ2B (0.56) | BAZ2BBAZ2AALDH1A1CYP1A2GAA | |
| SCHEMBL21060866 | 0.76 | BAZ2B (0.56) | BAZ2BBAZ2AALDH1A1CYP1A2GAA | |
| SCHEMBL70354 | 0.76 | BAZ2B (0.71) | BAZ2BBAZ2AALDH1A1CYP1A2GAA | |
| SCHEMBL5202768 | 0.76 | BAZ2B (0.56) | BAZ2BBAZ2AALDH1A1CYP1A2GAA | |
| Hydrochloric Acid SCHEMBL653318 | 0.76 | BAZ2B (0.51) | BAZ2BBAZ2AALDH1A1CYP1A2GAA | |
| SCHEMBL20763689 | 0.74 | BAZ2B (0.54) | BAZ2BBAZ2AALDH1A1CYP1A2GAA | |
| SCHEMBL1298467 | 0.74 | BAZ2B (0.54) | BAZ2BBAZ2AALDH1A1CYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3837252-B1 | HETEROAROMATIC CARBOXAMIDE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2025-12-10 | — | — | EP | disclosed |
| US-10695334-B2 | Heteroaromatic carboxamide derivatives as plasma kallikrein inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-06-30 | — | — | US | disclosed |
| US-20200054617-A1 | Heteroaromatic Carboxamide Derivatives as Plasma Kallikrein Inhibitors | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200054617-A1 | Heteroaromatic Carboxamide Derivatives as Plasma Kallikrein Inhibitors | KLKB1, KLK1, KLK5 | BAZ2B 1422/4885BAZ2A 1637/4885ALDH1A1 1415/4885 |
| US-10695334-B2 | Heteroaromatic carboxamide derivatives as plasma kallikrein inhibitors | KLKB1, KLK1, KLK5 | BAZ2B 1422/4885BAZ2A 1637/4885ALDH1A1 1415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.