Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | F13A1 | P00488 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | TGM1 | P22735 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5228286 | 0.89 | MEN1 (0.42) | GRIN2BKDM4EALDH1A1GRM5POLB | |
| SCHEMBL5227957 | 0.80 | MEN1 (0.40) | GRIN2BKDM4EALDH1A1GRM5POLB | |
| SCHEMBL5229398 | 0.72 | MEN1 (0.43) | GRIN2BKDM4EALDH1A1POLBMEN1 | |
| SCHEMBL17485677 | 0.71 | KDM4E (0.74) | GRIN2BKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL22213481 | 0.68 | CYP2C19 (0.43) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| SCHEMBL3795583 | 0.68 | MEN1 (0.69) | GRIN2BALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL10333902 | 0.66 | — | — | |
| SCHEMBL16611992 | 0.66 | KMT2A (0.67) | GRIN2BALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL3970912 | 0.66 | MEN1 (0.76) | GRIN2BALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL4814264 | 0.66 | MEN1 (0.76) | GRIN2BALDH1A1MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001970-A1 | DIPEPTIDE DERIVATIVES AS GROWTH HORMONE SECRETAGOGUES | PFIZER INC. (US) | 2000-05-24 | — | — | EP | disclosed |
| WO-1998058947-A1 | DIPEPTIDE DERIVATIVES AS GROWTH HORMONE SECRETAGOGUES | PFIZER INC. (US) | 1998-12-30 | — | — | WO | disclosed |