Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8105918 | 0.90 | CTSS (0.38) | FAAHTRPV1MEN1KMT2APOLB | |
| SCHEMBL8099403 | 0.83 | MEN1 (0.38) | DRD2DRD3MEN1KMT2AHDAC11 | |
| SCHEMBL8097661 | 0.82 | ANO1 (0.38) | MEN1KMT2APOLBNOTUMLMNA | |
| SCHEMBL8106103 | 0.81 | LMNA (0.48) | POLBCCR2LMNAMAPTALOX12 | |
| SCHEMBL2053916 | 0.80 | MEN1 (0.38) | MEN1KMT2APOLBNOTUMCCR2 | |
| SCHEMBL8090122 | 0.80 | MEN1 (0.39) | MEN1KMT2APOLBNOTUMCCR2 | |
| SCHEMBL8103463 | 0.80 | EPHX2 (0.48) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8104045 | 0.80 | NPSR1 (0.46) | MEN1KMT2APOLBCCR2LMNA | |
| SCHEMBL8105021 | 0.78 | ELANE (0.41) | MEN1KMT2A | |
| SCHEMBL8103239 | 0.78 | MEN1 (0.35) | MEN1KMT2APOLBNOTUMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |