Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28401796 | 0.80 | ALDH1A1 (0.48) | ALDH1A1TSHRTRPA1HDAC8TDP1 | |
| SCHEMBL14366693 | 0.80 | CA12 (0.32) | — | |
| Styrene SCHEMBL28935355 | 0.78 | ALDH1A1 (0.42) | ALDH1A1TSHRHDAC8 | |
| SCHEMBL2770902 | 0.77 | ALDH1A1 (0.44) | ALDH1A1TSHRTRPA1HDAC8TDP1 | |
| SCHEMBL6752546 | 0.76 | ALDH1A1 (0.55) | ALDH1A1TSHRTRPA1HDAC8TDP1 | |
| SCHEMBL28393090 | 0.75 | ALDH1A1 (0.42) | ALDH1A1TSHRTRPA1HDAC8TDP1 | |
| SCHEMBL2772762 | 0.74 | ALDH1A1 (0.41) | ALDH1A1TSHRTRPA1HDAC8TDP1 | |
| SCHEMBL1783186 | 0.73 | ALDH1A1 (0.58) | ALDH1A1TSHRTRPA1HDAC8TDP1 | |
| SCHEMBL8380695 | 0.72 | ALDH1A1 (0.39) | ALDH1A1TSHRHDAC8CHRNB2CHRNB4 | |
| SCHEMBL6548417 | 0.72 | ALDH1A1 (0.39) | ALDH1A1TSHRTRPA1HDAC8CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136886-A | RUBBER | KABUSHIKI KAISHA SHOFU (JP) | 2000-10-24 | — | — | US | disclosed |
| US-6063830-A | SILICA AND URETHANEACRYLATE | KABUSHIKI KAISHA SHOFU (JP) | 2000-05-16 | — | — | US | disclosed |
| US-5250615-A | Slidability; abrasion, weather, cold and impact resistance | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1993-10-05 | — | — | US | disclosed |
| US-5147947-A | Graft polymer containing vinyl monomer; friction resistance | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1992-09-15 | — | — | US | disclosed |
| EP-0367219-A2 | Polyorganosiloxane series thermoplastic resin and composition thereof | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1990-05-09 | — | — | EP | disclosed |