SCHEMBL6548417

SCHEMBL6548417

C=Cc1ccc([SiH](CCC)OC)cc1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
CHRNB2 P17787 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA7 P36544 1/20 0.36
CHRNA4 P43681 1/20 0.36
TAS1R3 Q7RTX0 2/20 0.33
TAS1R1 Q7RTX1 2/20 0.33
TRPA1 O75762 1/20 0.33
HDAC8 Q9BY41 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28393090 0.85 ALDH1A1 (0.42) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL28662217 0.77 ALDH1A1 (0.46) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL3482044 0.75 TP53 (0.32)
SCHEMBL8103451 0.72 ALDH1A1 (0.50) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL28401796 0.71 ALDH1A1 (0.48) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
Butane SCHEMBL28268770 0.71 ALDH1A1 (0.69) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
Styrene SCHEMBL28009679 0.70 ALDH1A1 (0.48) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL2772762 0.69 ALDH1A1 (0.41) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL28955922 0.69 LMNA (0.38) ALDH1A1TSHR
SCHEMBL10613551 0.69 ALDH1A1 (0.50) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1383469-A1 HAIR TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2004-01-28 EP disclosed
EP-1383860-A1 FABRIC CARE COMPOSITIONS Unilever Plc (GB) 2004-01-28 EP disclosed
EP-1383470-A2 HAIR TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2004-01-28 EP disclosed
WO-2002087523-A2 HAIR TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2002-11-07 WO disclosed
WO-2002087525-A1 HAIR TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2002-11-07 WO disclosed
WO-2002088293-A1 FABRIC CARE COMPOSITIONS UNILEVER PLC (GB) 2002-11-07 WO disclosed