Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | FNTA | P49354 | 12/20 | 0.55 |
| ▸ | FNTB | P49356 | 12/20 | 0.55 |
| ▸ | PGGT1B | P53609 | 11/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423622 | 1.00 | ALDH1A1 (0.57) | ALDH1A1FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL8104389 | 1.00 | ALDH1A1 (0.57) | ALDH1A1FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL6003187 | 0.91 | FNTA (0.55) | ALDH1A1FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL8436859 | 0.91 | FNTA (0.55) | ALDH1A1FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL8097870 | 0.88 | CYP11B1 (0.53) | ALDH1A1FNTAFNTBPGGT1BCYP11B1 | |
| SCHEMBL8534851 | 0.88 | CYP11B1 (0.53) | ALDH1A1FNTAFNTBPGGT1BCYP11B1 | |
| SCHEMBL8095394 | 0.87 | FNTA (0.60) | FNTAFNTBPGGT1BKCNH2CYP11B1 | |
| SCHEMBL8097798 | 0.86 | FNTA (0.49) | FNTAFNTBPGGT1BKCNH2CYP11B1 | |
| SCHEMBL5306125 | 0.85 | FNTA (0.51) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8607820 | 0.85 | FNTA (0.51) | FNTAFNTBPGGT1BCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127366-A | ANTICARCINOGENIC OR ANTITUMOR AGENTS | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |