Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | FNTA | P49354 | 6/20 | 0.49 |
| ▸ | FNTB | P49356 | 6/20 | 0.49 |
| ▸ | PGGT1B | P53609 | 6/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097870 | 1.00 | CYP11B1 (0.53) | CYP11B1CYP11B2KMT2AALDH1A1TSHR | |
| SCHEMBL6003187 | 0.90 | FNTA (0.55) | CYP11B1CYP11B2KMT2AALDH1A1FNTA | |
| SCHEMBL8436859 | 0.90 | FNTA (0.55) | CYP11B1CYP11B2KMT2AALDH1A1FNTA | |
| SCHEMBL5285086 | 0.88 | MAPK1 (0.48) | CYP11B1CYP11B2KMT2ATSHRFNTA | |
| SCHEMBL8423622 | 0.88 | ALDH1A1 (0.57) | CYP11B1CYP11B2ALDH1A1FNTAFNTB | |
| SCHEMBL7513048 | 0.88 | MAPK1 (0.48) | CYP11B1CYP11B2KMT2ATSHRFNTA | |
| SCHEMBL8104389 | 0.88 | ALDH1A1 (0.57) | CYP11B1CYP11B2ALDH1A1FNTAFNTB | |
| SCHEMBL8103587 | 0.88 | ALDH1A1 (0.57) | CYP11B1CYP11B2ALDH1A1FNTAFNTB | |
| SCHEMBL5298259 | 0.86 | FNTA (0.51) | CYP11B1CYP11B2ALDH1A1FNTAFNTB | |
| SCHEMBL8434426 | 0.86 | FNTA (0.51) | CYP11B1CYP11B2ALDH1A1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817678-A | IMIDAZOLE-CONTAINING PIPERIDINE DERIVATIVES, PEPTIDEMIMETIC | MERCK & CO., INC. (US) | 1998-10-06 | — | — | US | disclosed |