Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.38 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.38 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.38 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL8103701 | 0.79 | KMT2A (0.47) | MTNR1AMTNR1BMEN1KMT2AL3MBTL1 | |
| SCHEMBL7321839 | 0.79 | MME (0.45) | MME | |
| SCHEMBL8894806 | 0.76 | KMT2A (0.43) | MTNR1AMTNR1BMEN1KMT2AL3MBTL1 | |
| SCHEMBL9469991 | 0.74 | MEN1 (0.33) | MMEMEN1KMT2A | |
| SCHEMBL5702726 | 0.74 | MME (0.41) | MMEMEN1KMT2A | |
| SCHEMBL5702723 | 0.74 | MME (0.41) | MMEMEN1KMT2A | |
| SCHEMBL9469250 | 0.73 | L3MBTL1 (0.46) | MMEL3MBTL1 | |
| SCHEMBL7412653 | 0.73 | L3MBTL1 (0.40) | MMEL3MBTL1 | |
| SCHEMBL9470030 | 0.73 | MME (0.36) | MMEKMT2AHSD11B1 | |
| SCHEMBL9367708 | 0.72 | MME (0.32) | MMEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733642-B1 | Benzazepin-, benzoxazepin- and benzothiazepin-N-acetic acid-derivatives, their preparation and their pharmaceutical compositions | SOLVAY PHARM GMBH (DE) | 2000-11-29 | — | — | EP | disclosed |
| US-5677297-A | ENZYME INHIBITOR FOR TREATING THE HEART FAILURE TO REDUCE THE CARDIAC PRESSURE, DIURETICS | SOLVAY PHARMACEUTICALS GMBH (DE) | 1997-10-14 | — | — | US | disclosed |
| EP-0733642-A1 | Benzazepin-, benzoxazepin- and benzothiazepin-N-acetic acid-derivatives, their preparation and their pharmaceutical compositions | Kali-Chemie Pharma GmbH (DE) | 1996-09-25 | — | — | EP | disclosed |