Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 14/20 | 0.69 |
| ▸ | MAPK13 | O15264 | 7/20 | 0.69 |
| ▸ | MAPK12 | P53778 | 7/20 | 0.69 |
| ▸ | MAPK11 | Q15759 | 7/20 | 0.69 |
| ▸ | RAF1 | P04049 | 4/20 | 0.69 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.64 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GCGR | P47871 | 3/20 | 0.54 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.50 |
| ▸ | CSNK1E | P49674 | 3/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2647655 | 0.84 | MAPK14 (0.89) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL1387860 | 0.82 | KDM4E (0.83) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL4584994 | 0.81 | ALOX5 (0.63) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL4552012 | 0.79 | MAPK14 (0.67) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL6465619 | 0.79 | MAPK13 (0.90) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL1388055 | 0.79 | KDM4E (0.50) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL15676753 | 0.79 | NPY5R (0.61) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL18041548 | 0.78 | TGFBR1 (1.00) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL6469564 | 0.78 | MAPK13 (0.78) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL2647720 | 0.78 | MAPK13 (0.78) | MAPK14MAPK13MAPK12MAPK11RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021173-A1 | USE OF CSAID?TM COMPOUNDS FOR THE MANAGEMENT OF UTERINE CONTRACTIONS | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2000-07-26 | — | — | EP | disclosed |
| WO-1999018942-A1 | USE OF CSAIDTM COMPOUNDS FOR THE MANAGEMENT OF UTERINE CONTRACTIONS | IMPERIAL COLLEGE INNOVATIONS LTD. (GB) | 1999-04-22 | — | — | WO | disclosed |