Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cetyl Palmitate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | DGKA | P23743 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.56 |
| ▸ | NAAA | Q02083 | 1/20 | 0.56 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.56 |
| ▸ | PRKCA | P17252 | 1/20 | 0.55 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.55 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.55 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL10635385 | 0.97 | MAPT (0.63) | MAPTDGKALMNAKDM4EDUSP3 | |
| Glycol Distearate SCHEMBL7615343 | 0.95 | DGKA (0.75) | MAPTDGKALMNAKDM4EDUSP3 | |
| Ethylene Glycol Dioctanoate SCHEMBL751266 | 0.95 | DGKA (0.75) | MAPTDGKALMNAKDM4EDUSP3 | |
| Propylene Glycol SCHEMBL747502 | 0.95 | DGKA (0.75) | MAPTDGKALMNAKDM4EDUSP3 | |
| Stearic Acid SCHEMBL1565480 | 0.94 | MAPT (0.59) | MAPTDGKALMNAKDM4EDUSP3 | |
| Propylene Glycol SCHEMBL10781715 | 0.93 | MAPT (0.61) | MAPTDGKALMNAKDM4EDUSP3 | |
| Nonanoate SCHEMBL11334380 | 0.91 | MAPT (0.59) | MAPTDGKALMNAKDM4EDUSP3 | |
| Glycerin SCHEMBL14562870 | 0.90 | KDM4E (0.73) | MAPTDGKALMNAKDM4EDUSP3 | |
| Glycerin SCHEMBL394035 | 0.90 | KDM4E (0.73) | MAPTDGKALMNAKDM4EDUSP3 | |
| Glycerin SCHEMBL7895803 | 0.90 | KDM4E (0.73) | MAPTDGKALMNAKDM4EDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0897300-A4 | TREATMENT OF PRURITUS WITH VITAMIN D AND ANALOGS THEREOF | STRUBE MARILYN (US) | 2000-07-05 | — | — | EP | disclosed |
| EP-0897300-A1 | TREATMENT OF PRURITUS WITH VITAMIN D AND ANALOGS THEREOF | Strube, Marilyn (US) | 1999-02-24 | — | — | EP | disclosed |
| WO-1997013518-A1 | TREATMENT OF PRURITUS WITH VITAMIN D AND ANALOGS THEREOF | STRUBE MARILYN (US) | 1997-04-17 | — | — | WO | disclosed |