Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8109749 | 0.89 | OPRM1 (0.62) | SLC6A4ADRA1DOPRM1OPRK1OPRL1 | |
| SCHEMBL4670916 | 0.83 | APP (0.63) | SLC6A4OPRM1OPRK1OPRL1APP | |
| Hydrochloric Acid SCHEMBL7866348 | 0.82 | APP (0.62) | SLC6A4ADRA1DOPRM1OPRK1OPRL1 | |
| SCHEMBL27573221 | 0.79 | AVPR1A (0.60) | SLC6A4OPRM1OPRK1OPRL1IDO1 | |
| SCHEMBL4675208 | 0.79 | HTR2C (0.62) | SLC6A4OPRM1OPRK1OPRL1IDO1 | |
| SCHEMBL8103889 | 0.78 | SLC6A4 (0.51) | SLC6A4ADRA1DOPRM1OPRK1OPRL1 | |
| SCHEMBL18324824 | 0.78 | SLC6A4 (0.53) | SLC6A4OPRM1OPRK1OPRL1IDO1 | |
| SCHEMBL16801526 | 0.78 | KDM4E (0.69) | SLC6A4OPRM1OPRK1OPRL1IDO1 | |
| Hydrochloric Acid SCHEMBL7867871 | 0.77 | HTR2C (0.63) | SLC6A4OPRM1OPRK1OPRL1IDO1 | |
| SCHEMBL4675206 | 0.77 | SLC6A4 (0.58) | SLC6A4OPRM1OPRK1OPRL1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143744-A | Sulfamide-metalloprotease inhibitors | SYNTEX (U.S.A.) INC. (US) | 2000-11-07 | — | — | US | disclosed |
| US-6130220-A | ENZYME INHIBITORS | SYNTEX (USA) INC. (US) | 2000-10-10 | — | — | US | disclosed |