Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.62 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103890 | 0.89 | SLC6A4 (0.53) | OPRM1OPRK1OPRL1SLC6A4ADRA1D | |
| SCHEMBL18474132 | 0.86 | SLC6A4 (0.60) | OPRM1OPRK1OPRL1SLC6A4HTR1A | |
| SCHEMBL8103916 | 0.84 | CYP1A2 (0.71) | OPRM1OPRK1OPRL1SLC6A4HTR1A | |
| SCHEMBL8109656 | 0.84 | OPRM1 (0.68) | OPRM1OPRK1OPRL1SLC6A4HTR1A | |
| SCHEMBL8096608 | 0.84 | HTR1D (0.53) | OPRM1OPRK1OPRL1SLC6A4HTR1A | |
| SCHEMBL4674422 | 0.83 | HTR1D (0.71) | OPRM1OPRK1OPRL1SLC6A4HTR1A | |
| SCHEMBL8103895 | 0.81 | SLC6A4 (0.69) | SLC6A4HTR1AHTR1B | |
| SCHEMBL4769253 | 0.79 | OPRM1 (0.63) | OPRM1OPRK1OPRL1SLC6A4HTR1A | |
| SCHEMBL2781047 | 0.79 | HTR2C (0.62) | OPRM1OPRK1OPRL1SLC6A4HTR1A | |
| SCHEMBL8149530 | 0.78 | SLC6A4 (0.51) | OPRM1OPRK1OPRL1SLC6A4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143744-A | Sulfamide-metalloprotease inhibitors | SYNTEX (U.S.A.) INC. (US) | 2000-11-07 | — | — | US | disclosed |
| US-6130220-A | ENZYME INHIBITORS | SYNTEX (USA) INC. (US) | 2000-10-10 | — | — | US | disclosed |