Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.52 |
| ▸ | MGLL | Q99685 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8149182 | 0.82 | MGLL (0.67) | MGLLLMNATP53MAPTL3MBTL1 | |
| SCHEMBL8103919 | 0.78 | KDM2B (0.47) | KDM2BMGLLLMNAALDH1A1HTT | |
| SCHEMBL8109746 | 0.78 | MGLL (0.58) | MGLLLMNATP53MAPTL3MBTL1 | |
| SCHEMBL4671259 | 0.75 | MGLL (0.65) | MGLLLMNATP53MAPTL3MBTL1 | |
| SCHEMBL8103874 | 0.75 | LMNA (0.53) | KDM2BMGLLLMNATP53MAPT | |
| SCHEMBL8140791 | 0.73 | MGLL (0.62) | MGLLLMNATP53MAPTL3MBTL1 | |
| SCHEMBL8109771 | 0.73 | KMT2A (0.69) | MGLLLMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8106361 | 0.73 | LMNA (0.58) | MGLLLMNATP53MAPTL3MBTL1 | |
| SCHEMBL2322628 | 0.72 | MGLL (0.64) | KDM2BMGLLLMNATP53MAPT | |
| SCHEMBL3391998 | 0.72 | MGLL (0.69) | MGLLLMNATP53MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143744-A | Sulfamide-metalloprotease inhibitors | SYNTEX (U.S.A.) INC. (US) | 2000-11-07 | — | — | US | disclosed |
| US-6130220-A | ENZYME INHIBITORS | SYNTEX (USA) INC. (US) | 2000-10-10 | — | — | US | disclosed |
| US-5998412-A | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | SYNTEX (U.S.A.) INC. (US) | 1999-12-07 | — | — | US | disclosed |