Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 7/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670619 | 0.84 | MGLL (0.55) | LMNATP53MAPTL3MBTL1MGLL | |
| SCHEMBL8109746 | 0.81 | MGLL (0.58) | LMNATP53MAPTL3MBTL1MGLL | |
| SCHEMBL8153997 | 0.80 | KDM2B (0.41) | LMNATP53MAPTL3MBTL1MGLL | |
| SCHEMBL14637904 | 0.80 | LMNA (0.59) | LMNATP53MAPTL3MBTL1MGLL | |
| SCHEMBL8147775 | 0.80 | KDM2B (0.64) | LMNATP53MAPTL3MBTL1MGLL | |
| SCHEMBL28512371 | 0.80 | LMNA (0.70) | LMNAMAPTMGLLTSHRSMN1; SMN2 | |
| SCHEMBL8149182 | 0.77 | MGLL (0.67) | LMNATP53MAPTL3MBTL1MGLL | |
| SCHEMBL8140791 | 0.77 | MGLL (0.62) | LMNATP53MAPTL3MBTL1MGLL | |
| SCHEMBL14638479 | 0.76 | MGLL (0.61) | LMNATP53MAPTL3MBTL1MGLL | |
| SCHEMBL8106361 | 0.76 | LMNA (0.58) | LMNATP53MAPTL3MBTL1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143744-A | Sulfamide-metalloprotease inhibitors | SYNTEX (U.S.A.) INC. (US) | 2000-11-07 | — | — | US | disclosed |
| US-6130220-A | ENZYME INHIBITORS | SYNTEX (USA) INC. (US) | 2000-10-10 | — | — | US | disclosed |
| US-5998412-A | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | SYNTEX (U.S.A.) INC. (US) | 1999-12-07 | — | — | US | disclosed |