Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 4/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7456278 | 0.89 | DRD3 (0.50) | ALDH1A1GAATSHRHSD17B10DRD3 | |
| SCHEMBL7443295 | 0.88 | FYN (0.45) | ALDH1A1GAATSHRHSD17B10DRD3 | |
| SCHEMBL7451624 | 0.88 | FYN (0.45) | ALDH1A1GAATSHRHSD17B10DRD3 | |
| SCHEMBL7451070 | 0.88 | DRD2 (0.50) | ALDH1A1GAATSHRHSD17B10DRD3 | |
| SCHEMBL8108298 | 0.86 | KDM4E (0.48) | ALDH1A1TSHRHSD17B10DRD3HTR1A | |
| SCHEMBL7448310 | 0.86 | DRD3 (0.48) | DRD3HTR1ADRD2DRD4 | |
| SCHEMBL7451238 | 0.86 | DRD2 (0.51) | ALDH1A1GAADRD3DRD2DRD4 | |
| SCHEMBL7454943 | 0.85 | ALDH1A1 (0.52) | ALDH1A1DRD3HTR1ADRD2DRD4 | |
| SCHEMBL7448204 | 0.85 | FYN (0.42) | ALDH1A1GAATSHRHSD17B10DRD3 | |
| SCHEMBL7456265 | 0.84 | DRD3 (0.54) | ALDH1A1DRD3HTR1AFYNDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6084130-A | FOR TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-04 | — | — | US | disclosed |