Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.55 |
| ▸ | RBP4 | P02753 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MGLL | Q99685 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | BCR | P11274 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12803049 | 0.86 | HIF1A (0.55) | POLBLMNAHPGDMEN1KMT2A | |
| SCHEMBL2295165 | 0.85 | LMNA (0.74) | POLBLMNAHPGDHSD11B1RBP4 | |
| SCHEMBL11480218 | 0.81 | HPGD (1.00) | POLBLMNAHPGDHSD11B1RBP4 | |
| SCHEMBL1534279 | 0.81 | HIF1A (0.50) | POLBLMNAHPGDMGLLCYP3A4 | |
| SCHEMBL12959479 | 0.80 | HIF1A (0.49) | POLBLMNAHPGDMEN1KMT2A | |
| SCHEMBL7581128 | 0.79 | POLB (0.74) | POLBLMNAHPGDHSD11B1RBP4 | |
| SCHEMBL13503960 | 0.79 | POLB (0.74) | POLBLMNAHPGDHSD11B1RBP4 | |
| SCHEMBL14223339 | 0.79 | POLB (0.74) | POLBLMNAHPGDHSD11B1RBP4 | |
| SCHEMBL8098770 | 0.78 | LMNA (0.57) | LMNAMEN1KMT2AALDH1A1GAA | |
| SCHEMBL8094577 | 0.78 | TRPA1 (0.54) | POLBLMNAHPGDALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008150447-A1 | AMIDE COMPOUNDS AND THE USE THEREOF | EURO-CELTIQUE S.A. (LU) | 2008-12-11 | — | — | WO | disclosed |