Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | GOT1 | P17174 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CCR2 | P41597 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2291409 | 0.86 | LMNA (0.60) | LMNAHTTGAAMAPTTRPV1 | |
| SCHEMBL30986029 | 0.83 | RAB9A (0.76) | LMNAHTTGAAMAPTTRPV1 | |
| SCHEMBL19745233 | 0.81 | RAB9A (0.64) | LMNAHTTGAAMAPTTRPV1 | |
| SCHEMBL4302538 | 0.81 | LMNA (0.72) | LMNAHTTGAAMAPTTRPV1 | |
| SCHEMBL2384223 | 0.81 | POLB (0.61) | LMNAHTTGAAMAPTTRPV1 | |
| SCHEMBL2294293 | 0.80 | GRIN2B (0.50) | LMNAHTTGAAMAPTTRPV1 | |
| SCHEMBL8104004 | 0.78 | POLB (0.68) | LMNAGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL5912834 | 0.78 | EPHX2 (0.60) | LMNAHTTGAAMAPTTRPV1 | |
| SCHEMBL4395452 | 0.76 | FAAH (0.63) | LMNAHTTGAAMAPTTRPV1 | |
| SCHEMBL4552460 | 0.76 | FAAH (0.53) | LMNAHTTGAAMAPTTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008150447-A1 | AMIDE COMPOUNDS AND THE USE THEREOF | EURO-CELTIQUE S.A. (LU) | 2008-12-11 | — | — | WO | disclosed |