SCHEMBL8104286

SCHEMBL8104286

O=c1[nH]c(=O)n(C2CC[C@@H](CO)O2)cc1F

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.62
SMN1; SMN2 Q16637 3/20 0.62
MAPT P10636 2/20 0.56
ESR1 P03372 1/20 0.56
ALB P02768 2/20 0.47
ALDH1A1 P00352 1/20 0.47
MAPK1 P28482 1/20 0.47
TSHR P16473 1/20 0.47
PMP22 Q01453 1/20 0.47
HBB P68871 1/20 0.47
ALOX12 P18054 1/20 0.44
ADRA1A P35348 1/20 0.44
TK1 P04183 2/20 0.43
PKM P14618 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26296051 1.00 LMNA (0.62) LMNASMN1; SMN2MAPTESR1ALB
SCHEMBL3437129 1.00 LMNA (0.62) LMNASMN1; SMN2MAPTESR1ALB
SCHEMBL3437131 1.00 LMNA (0.62) LMNASMN1; SMN2MAPTESR1ALB
SCHEMBL21345305 1.00 LMNA (0.62) LMNASMN1; SMN2MAPTESR1ALB
Phosphoric Acid SCHEMBL7906707 0.95 LMNA (0.57) LMNASMN1; SMN2MAPTESR1ALB
SCHEMBL21345988 0.87 LMNA (0.47) LMNASMN1; SMN2MAPTESR1ALB
SCHEMBL19657129 0.85 LMNA (0.48) LMNASMN1; SMN2ALBALDH1A1MAPK1
SCHEMBL23485 0.85 LMNA (0.58) LMNAALBALDH1A1TSHRPMP22
SCHEMBL14596607 0.85 LMNA (0.58) LMNAALBALDH1A1TSHRPMP22
SCHEMBL22992337 0.85 LMNA (0.58) LMNAALBALDH1A1TSHRPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010052243-A2 NEUROTENSIN-DERIVED BRANCHED PEPTIDES AND USES THEREOF BRACCI LUISA (IT) 2010-05-14 WO disclosed
US-6040297-A A THERAPEUTIC AGENTS TREATING TUMORS AND RETROVIRAL INFECTIONS INCLUDING HIV INFECTIONS BIOSEARCH ITALIA, S.P.A. (IT) 2000-03-21 US disclosed