Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.46 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.46 |
| ▸ | TK1 | P04183 | 2/20 | 0.44 |
| ▸ | ALB | P02768 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3437131 | 0.95 | LMNA (0.62) | LMNASMN1; SMN2MAPTESR1TK1 | |
| SCHEMBL26296051 | 0.95 | LMNA (0.62) | LMNASMN1; SMN2MAPTESR1TK1 | |
| SCHEMBL3437129 | 0.95 | LMNA (0.62) | LMNASMN1; SMN2MAPTESR1TK1 | |
| SCHEMBL21345305 | 0.95 | LMNA (0.62) | LMNASMN1; SMN2MAPTESR1TK1 | |
| SCHEMBL8104286 | 0.95 | LMNA (0.62) | LMNASMN1; SMN2MAPTESR1TK1 | |
| Phosphoric Acid SCHEMBL5147665 | 0.86 | TK1 (0.58) | LMNATK1ALBALDH1A1TSHR | |
| Phosphoric Acid SCHEMBL5709986 | 0.86 | TK1 (0.58) | LMNATK1ALBALDH1A1TSHR | |
| Phosphoric Acid SCHEMBL7977953 | 0.86 | TK1 (0.58) | LMNATK1ALBALDH1A1TSHR | |
| Phosphoric Acid SCHEMBL18249308 | 0.86 | TK1 (0.58) | LMNATK1ALBALDH1A1TSHR | |
| Phosphoric Acid SCHEMBL3691397 | 0.85 | ALDH1A1 (0.51) | LMNASMN1; SMN2P2RY6TK1ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194141-B1 | DETECTING MODULATOR OF VIRAL PROPAGATION; INCUBATE VIRAL NUCLEOTIDE SEQUENCE MIXTURE WITH METALS, INCUBATE SECOND MIXTURE WITH MODULATOR, CALIBRATE AND COMPARE AMOUNT OF URIDINE INCORPORATED INTO TRANSCRIPTS IN BOTH MIXTURES | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2001-02-27 | — | — | US | disclosed |