Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | ALB | P02768 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TK1 | P04183 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL25262791 | 0.88 | TK1 (0.57) | LMNAALBALDH1A1TK1TSHR | |
| SCHEMBL14421795 | 0.86 | LMNA (0.58) | LMNAALBALDH1A1TK1TSHR | |
| SCHEMBL925743 | 0.86 | LMNA (0.58) | LMNAALBALDH1A1TK1TSHR | |
| SCHEMBL29711774 | 0.86 | LMNA (0.58) | LMNAALBALDH1A1TK1TSHR | |
| SCHEMBL23485 | 0.86 | LMNA (0.58) | LMNAALBALDH1A1TK1TSHR | |
| SCHEMBL14596607 | 0.86 | LMNA (0.58) | LMNAALBALDH1A1TK1TSHR | |
| SCHEMBL13286394 | 0.86 | LMNA (0.58) | LMNAALBALDH1A1TK1TSHR | |
| SCHEMBL762579 | 0.86 | LMNA (0.58) | LMNAALBALDH1A1TK1TSHR | |
| SCHEMBL22992337 | 0.86 | LMNA (0.58) | LMNAALBALDH1A1TK1TSHR | |
| SCHEMBL27505365 | 0.86 | LMNA (0.58) | LMNAALBALDH1A1TK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201585-A1 | MODULATORS OF DUX4 FOR REGULATION OF MUSCLE FUNCTION | GENEA IP HOLDINGS PTY LTD (AU) | 2017-11-30 | — | — | WO | disclosed |