Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5689585 | 0.80 | RAB9A (0.45) | SMN1; SMN2RAB9AKDM4EALDH1A1KMT2A | |
| SCHEMBL5689580 | 0.80 | RAB9A (0.45) | SMN1; SMN2RAB9AKDM4EALDH1A1KMT2A | |
| SCHEMBL6136724 | 0.80 | RAB9A (0.45) | SMN1; SMN2RAB9AKDM4EALDH1A1KMT2A | |
| SCHEMBL4585228 | 0.77 | SMN1; SMN2 (0.39) | SMN1; SMN2RAB9AKDM4EALDH1A1KMT2A | |
| SCHEMBL4585225 | 0.77 | SMN1; SMN2 (0.39) | SMN1; SMN2RAB9AKDM4EALDH1A1KMT2A | |
| SCHEMBL4585219 | 0.77 | SMN1; SMN2 (0.39) | SMN1; SMN2RAB9AKDM4EALDH1A1KMT2A | |
| SCHEMBL5691476 | 0.69 | CYP1A2 (0.55) | SMN1; SMN2RAB9AKDM4EALDH1A1KMT2A | |
| SCHEMBL5691469 | 0.69 | CYP1A2 (0.55) | SMN1; SMN2RAB9AKDM4EALDH1A1KMT2A | |
| SCHEMBL6136526 | 0.66 | RAB9A (0.45) | SMN1; SMN2RAB9AKDM4EALDH1A1KMT2A | |
| SCHEMBL6136518 | 0.66 | RAB9A (0.45) | SMN1; SMN2RAB9AKDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090942-A | Process and intermediates for a β3 -adrenergic receptor agonist | PFIZER INC. (US) | 2000-07-18 | — | — | US | disclosed |