Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | DRD1 | P21728 | 2/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2831238 | 0.80 | CYP1A2 (0.38) | DRD1MAPT | |
| SCHEMBL7324971 | 0.80 | ALDH1A3 (0.46) | ALDH1A3ALDH1A1KDM4EDRD1CYP2A6 | |
| SCHEMBL4243856 | 0.77 | CHRNB4 (0.49) | KDM4E | |
| SCHEMBL1299966 | 0.77 | ALDH1A3 (0.62) | ALDH1A3ALDH1A1KDM4EDRD1CYP2A6 | |
| SCHEMBL11967027 | 0.75 | SMN1; SMN2 (0.51) | ALDH1A1STSLMNASMN1; SMN2MAPT | |
| SCHEMBL18920665 | 0.75 | CHRNB4 (0.44) | ALDH1A1LMNAHPGD | |
| SCHEMBL14016002 | 0.74 | ALDH1A3 (0.76) | ALDH1A3ALDH1A1KDM4EDRD1CYP2A6 | |
| SCHEMBL384361 | 0.74 | ALDH1A3 (1.00) | ALDH1A3ALDH1A1KDM4EDRD1CYP2A6 | |
| SCHEMBL18920686 | 0.73 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL6624087 | 0.73 | HRH3 (0.43) | ALDH1A1CYP2A6SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0605729-B1 | OXAZOLIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2000-07-26 | — | — | EP | disclosed |
| US-5480899-A | ANTILIPEMIC AGENTS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0605729-A1 | OXAZOLIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1994-07-13 | — | — | EP | disclosed |