Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8109010 | 0.91 | GAA (0.41) | GAAALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL8095057 | 0.91 | GAA (0.41) | GAAALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL8102848 | 0.91 | GAA (0.41) | GAAALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL8104715 | 0.88 | GAA (0.44) | GAAALDH1A1MAPK1L3MBTL1CACNA1B | |
| SCHEMBL8102902 | 0.88 | GAA (0.44) | GAAALDH1A1MAPK1L3MBTL1CACNA1B | |
| SCHEMBL8108806 | 0.88 | MAPT (0.36) | GAAALDH1A1MAPK1CACNA1BMAPT | |
| SCHEMBL8108807 | 0.82 | CCR5 (0.39) | CCR5 | |
| SCHEMBL8535538 | 0.82 | SMN1; SMN2 (0.41) | GAAALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL8104565 | 0.82 | SMN1; SMN2 (0.41) | GAAALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL8104449 | 0.81 | ALDH1A1 (0.37) | GAAALDH1A1MAPTSMN1; SMN2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090802-A | BACTERICIDE | SANKYO COMPANY, LIMITED (JP) | 2000-07-18 | — | — | US | disclosed |
| EP-0882728-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-09 | — | — | EP | disclosed |