Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535538 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2PKMHTTALDH1A1HSD11B1 | |
| SCHEMBL8110563 | 0.89 | PKM (0.44) | SMN1; SMN2PKMHTTALDH1A1HSD11B1 | |
| SCHEMBL8104450 | 0.88 | SMN1; SMN2 (0.43) | SMN1; SMN2PKMHTTALDH1A1HSD11B1 | |
| SCHEMBL8436042 | 0.87 | SMN1; SMN2 (0.45) | SMN1; SMN2PKMHTTALDH1A1HSD11B1 | |
| SCHEMBL8435157 | 0.87 | SMN1; SMN2 (0.45) | SMN1; SMN2PKMHTTALDH1A1HSD11B1 | |
| SCHEMBL8104449 | 0.86 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1MAPTGAAGRIN2B | |
| SCHEMBL8104555 | 0.84 | HSD11B1 (0.44) | SMN1; SMN2PKMHTTALDH1A1HSD11B1 | |
| SCHEMBL8095391 | 0.84 | HSD11B1 (0.44) | SMN1; SMN2PKMHTTALDH1A1HSD11B1 | |
| SCHEMBL8104700 | 0.84 | HSD11B1 (0.44) | SMN1; SMN2PKMHTTALDH1A1HSD11B1 | |
| SCHEMBL8102742 | 0.84 | HSD11B1 (0.44) | SMN1; SMN2PKMHTTALDH1A1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090802-A | BACTERICIDE | SANKYO COMPANY, LIMITED (JP) | 2000-07-18 | — | — | US | disclosed |