SCHEMBL8104937

SCHEMBL8104937

C=CC(=O)NCc1ccc(Cl)c(Cl)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.61
TGM2 P21980 1/20 0.58
SMN1; SMN2 Q16637 2/20 0.55
ALDH1A1 P00352 3/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
HPGD P15428 1/20 0.52
LMNA P02545 4/20 0.52
TRPV1 Q8NER1 1/20 0.50
EPHX2 P34913 1/20 0.48
HRH3 Q9Y5N1 2/20 0.47
POLB P06746 1/20 0.47
TP53 P04637 1/20 0.47
HDAC4 P56524 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC7 Q8WUI4 1/20 0.47
HDAC11 Q96DB2 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
HDAC9 Q9UKV0 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7754179 0.87 TGM2 (0.55) TSHRTGM2HDAC8
SCHEMBL3544782 0.82 P2RX7 (0.52) TGM2TRPV1EPHX2
SCHEMBL732934 0.82 TGM2 (0.81) TSHRTGM2ALDH1A1MEN1KMT2A
SCHEMBL4927519 0.81 TGM2 (0.69) TGM2SMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL24575982 0.80 TSHR (0.71) TSHRSMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL31362165 0.79 TSHR (0.69) TSHRSMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL3169688 0.79 TSHR (0.69) TSHRSMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL11305715 0.79 TSHR (0.69) TSHRSMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL732581 0.79 TGM2 (0.61) TSHRTGM2ALDH1A1MEN1KMT2A
SCHEMBL8765259 0.79 GAA (0.53) TGM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6117821-A COMPRISING HERBICIDES AND AGRONOMICALLY ACCEPTABLE CARRIERS; USE THEREOF AS BROAD SPECTRUM HERBICIDES WHICH ARE EFFECTIVE AGAINST BOTH MONOCOT AND DICOT WEED SPECIES IN BOTH PREEMERGENCE AND POSTEMERGENCE APPLICATIONS ROHM AND HAAS COMPANY (US) 2000-09-12 US disclosed
US-6025301-A BROAD SPECTRUM HERBICIDES EFFECTIVE AGAINST BOTH MONOCOT AND DICOT WEED SPECIES IN POSTEMERGENCE APPLICATIONS ROHM AND HAAS COMPANY (US) 2000-02-15 US disclosed
US-5883044-A Herbicidal method utilizing phosphosulfonate herbicides and oxime ether safeners ROHM AND HAAS COMPANY (US) 1999-03-16 US disclosed
US-5866513-A Aryl-substituted cycloalkanes and cycloalkenes and herbicidal use thereof ROHM AND HAAS COMPANY (US) 1999-02-02 US disclosed
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP disclosed
EP-0862860-A2 Indanone herbicide compositions and use thereof ROHM AND HAAS COMPANY (US) 1998-09-09 EP disclosed
US-5733849-A Halopyridyl triazolinone herbicides and herbicidal use thereof ROHM AND HAAS COMPANY (US) 1998-03-31 US disclosed
US-5726124-A IN MIXTURE WITH OTHER HERBICIDES, ALKYLATION AND ETHERIFICATION OF PYRIMIDINONE AND THIOPYRIMIDINONE COMPOUNDS ROHM AND HAAS COMPANY (US) 1998-03-10 US disclosed
US-5723414-A APPLYING TO WEEDS ROHM AND HAAS COMPANY (US) 1998-03-03 US disclosed
US-5693590-A PLANT GROWTH REGULATOR ROHM AND HAAS COMPANY (US) 1997-12-02 US disclosed
US-4083713-A CONTROLLING WEEDS ROHM AND HAAS COMPANY (US) 1978-04-11 US disclosed
US-4082538-A HERBICIDES FOR MONOCOTYLEDONS AND DICOTYLEDONS ROHM AND HAAS COMPANY (US) 1978-04-04 US disclosed
US-4076741-A Herbicidal 4-trifluoromethyl-4-nitrodiphenyl ethers ROHM AND HAAS COMPANY (US) 1978-02-28 US disclosed
US-4070178-A Herbicidal diphenyl ethers ROHM AND HAAS COMPANY (US) 1978-01-24 US disclosed
US-4063929-A Herbicidal 4-trifluoromethyl-4'nitrodiphenyl ethers ROHM AND HAAS COMPANY (US) 1977-12-20 US disclosed
US-4059435-A Herbicidal 4-trifluoromethyl-3-cyanoalkoxy-4-nitro diphenyl ethers ROHM AND HAAS COMPANY (US) 1977-11-22 US disclosed
US-4046798-A Herbicidal 4-trifluoromethyl-4'nitrodiphenyl ethers ROHM AND HAAS COMPANY (US) 1977-09-06 US disclosed
US-4039588-A ALKOXY, AMINO, HALO-, OR CYANO-SUBSTITUTED ROHM AND HAAS COMPANY (US) 1977-08-02 US disclosed
US-3954875-A Benzophenone herbicides ROHM AND HAAS COMPANY (US) 1976-05-04 US disclosed
US-3950379-A HERBICIDES ROHM AND HAAS COMPANY (US) 1976-04-13 US disclosed