Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | TTR | P02766 | 5/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.44 |
| ▸ | CBR1 | P16152 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8480028 | 0.86 | MAPT (0.54) | FFAR1HPGDALDH1A1POLBGAA | |
| SCHEMBL12667945 | 0.82 | FFAR1 (1.00) | FFAR1CHRM1TDP1TTRFFAR4 | |
| SCHEMBL6924900 | 0.81 | FFAR1 (0.57) | FFAR1FFAR4 | |
| SCHEMBL8105348 | 0.80 | TTR (0.70) | FFAR1HPGDALDH1A1POLBGAA | |
| SCHEMBL7160901 | 0.77 | FFAR1 (0.60) | FFAR1 | |
| SCHEMBL1178304 | 0.77 | FFAR1 (0.51) | FFAR1FFAR4 | |
| SCHEMBL3652668 | 0.76 | MAPT (0.63) | HPGDALDH1A1POLBGAAL3MBTL1 | |
| SCHEMBL7398838 | 0.76 | GAA (0.59) | FFAR1ALDH1A1GAAL3MBTL1FFAR4 | |
| Hydrochloric Acid SCHEMBL11346813 | 0.75 | MAPT (0.67) | HPGDALDH1A1POLBGAAL3MBTL1 | |
| SCHEMBL28927554 | 0.74 | FFAR1 (0.69) | FFAR1CHRM1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0848703-B1 | DERIVATIVES OF BENZOSULPHONAMIDES AS INHIBITORS OF THE ENZYME CYCLO-OXYGENASE II | NYCOMED AUSTRIA GMBH (AT) | 2000-09-27 | — | — | EP | disclosed |