SCHEMBL12667945

SCHEMBL12667945

O=C(O)CCc1ccc(Oc2ccc(Cl)cc2Cl)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 9/20 1.00
PPARG P37231 2/20 0.57
PPARA Q07869 1/20 0.57
TDP1 Q9NUW8 1/20 0.51
MRGPRX4 Q96LA9 1/20 0.51
FFAR4 Q5NUL3 2/20 0.51
TTR P02766 2/20 0.50
CHRM1 P11229 1/20 0.50
SRD5A2 P31213 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18058921 0.87 FFAR1 (0.78) FFAR1PPARGPPARAFFAR4SRD5A2
SCHEMBL9036833 0.85 FFAR1 (0.74) FFAR1TDP1MRGPRX4TTRCHRM1
SCHEMBL8332044 0.83 FFAR1 (0.71) FFAR1PPARGPPARATDP1MRGPRX4
SCHEMBL18058920 0.83 FFAR1 (1.00) FFAR1PPARGPPARATDP1MRGPRX4
SCHEMBL8104954 0.82 FFAR1 (0.70) FFAR1TDP1MRGPRX4FFAR4TTR
SCHEMBL28927554 0.82 FFAR1 (0.69) FFAR1PPARGPPARAFFAR4CHRM1
SCHEMBL30172602 0.82 FFAR1 (0.69) FFAR1PPARGPPARAFFAR4CHRM1
SCHEMBL2171471 0.79 FFAR1 (0.65) FFAR1TTR
SCHEMBL9272097 0.78 FFAR1 (0.64) FFAR1TDP1MRGPRX4TTRCHRM1
SCHEMBL15211124 0.78 FFAR1 (0.72) FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118085061-A Cyclic peptide tyrosine compounds as neuropeptide y receptor modulators 詹森药业有限公司 2024-05-28 CN disclosed
CN-110099692-B Cyclic peptide tyrosine compounds as neuropeptide y receptor modulators 詹森药业有限公司 2024-03-12 CN disclosed
US-20160257701-A1 NOVEL HETEROCYCLIC COMPOUNDS CADILA HEALTHCARE LIMITED (IN) 2016-09-08 US disclosed
US-20110124503-A1 NOVEL HERBICIDE RESISTANCE GENES DOW AGROSCIENCES LLC (US) 2011-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110124503-A1 NOVEL HERBICIDE RESISTANCE GENES ALDH7A1, AGXT, AADAC FFAR1 1753/4885PPARG 912/4885PPARA 2256/4885
US-20160257701-A1 NOVEL HETEROCYCLIC COMPOUNDS GPR55, GPR68, GPR65 FFAR1 23/4885PPARG 70/4885PPARA 211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.