Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8110644 | 0.85 | AKR1C1 (0.59) | HDAC1OPRM1SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7366815 | 0.83 | HDAC1 (0.50) | HDAC1OPRM1SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL3520383 | 0.80 | AKR1C1 (0.62) | HDAC1SLC6A3SLC6A4SLC6A2AKR1C1 | |
| SCHEMBL27511149 | 0.80 | OPRM1 (0.51) | HDAC1OPRM1SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7371503 | 0.80 | HDAC1 (0.47) | HDAC1OPRM1SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL248544 | 0.78 | AKR1C1 (0.64) | HDAC1AKR1C1 | |
| SCHEMBL349729 | 0.77 | AKR1C1 (0.53) | HDAC1OPRM1SLC6A3SLC6A4HDAC3 | |
| SCHEMBL8848428 | 0.75 | ALDH1A1 (0.41) | SLC6A4SLC6A2 | |
| SCHEMBL6349290 | 0.74 | AKR1C1 (0.70) | HDAC1AKR1C1 | |
| SCHEMBL5138906 | 0.73 | AKR1C3 (0.33) | HDAC1OPRM1HDAC3HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124354-A | TREATMENT OF URINARY INCONTINENCE OR IRRITABLE BOWEL SYNDROME | PHARMACIA & UPJOHN AB (SE) | 2000-09-26 | — | — | US | disclosed |
| EP-0923536-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | Pharmacia & Upjohn Aktiebolag (SE) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998004517-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | PHARMACIA & UPJOHN AB (SE) | 1998-02-05 | — | — | WO | disclosed |