Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | LAP3 | P28838 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3945464 | 1.00 | HTT (0.38) | HTTBCHETRPA1IDO1LAP3 | |
| SCHEMBL9448041 | 0.88 | HTT (0.35) | HTTTRPA1 | |
| SCHEMBL9448189 | 0.86 | HTT (0.34) | HTTBCHE | |
| SCHEMBL9233442 | 0.83 | HTT (0.31) | HTT | |
| SCHEMBL9233445 | 0.83 | HTT (0.31) | HTT | |
| SCHEMBL5983969 | 0.80 | HTT (0.34) | HTTTRPA1 | |
| SCHEMBL7643397 | 0.80 | HTT (0.34) | HTTTRPA1 | |
| SCHEMBL8581628 | 0.79 | HTT (0.31) | HTT | |
| SCHEMBL9448155 | 0.79 | CTRB1 (0.31) | HTT | |
| SCHEMBL8423473 | 0.79 | HTT (0.37) | HTTBCHETRPA1IDO1LAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649854-B1 | Bisconjugates comprising two saccharides and a spacer | AKZO NOBEL NV (NL) | 2000-03-15 | — | — | EP | disclosed |
| EP-0649854-A1 | Bisconjugates comprising two saccharides and a spacer | Akzo Nobel N.V. (NL) | 1995-04-26 | — | — | EP | disclosed |
| EP-0532668-A1 | NOVEL -g(a)-GLUCOSIDASE INHIBITORS. | MERRELL DOW PHARMA (US) | 1993-03-24 | — | — | EP | disclosed |
| WO-1991018915-A1 | NOVEL α-GLUCOSIDASE INHIBITORS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-12-12 | — | — | WO | disclosed |