Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | CTSC | P53634 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8105080 | 0.86 | HTT (0.38) | HTTBCHE | |
| SCHEMBL3945464 | 0.86 | HTT (0.38) | HTTBCHE | |
| SCHEMBL9448041 | 0.82 | HTT (0.35) | HTT | |
| SCHEMBL5983969 | 0.74 | HTT (0.34) | HTT | |
| SCHEMBL7643397 | 0.74 | HTT (0.34) | HTT | |
| SCHEMBL9448155 | 0.74 | CTRB1 (0.31) | HTT | |
| SCHEMBL8423473 | 0.73 | HTT (0.37) | HTTBCHE | |
| SCHEMBL9093078 | 0.72 | HTT (0.36) | HTTBCHE | |
| SCHEMBL7639804 | 0.72 | HTT (0.36) | HTTBCHE | |
| SCHEMBL7636822 | 0.71 | TRPA1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532668-A1 | NOVEL -g(a)-GLUCOSIDASE INHIBITORS. | MERRELL DOW PHARMA (US) | 1993-03-24 | — | — | EP | disclosed |
| WO-1991018915-A1 | NOVEL α-GLUCOSIDASE INHIBITORS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-12-12 | — | — | WO | disclosed |