Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3945464 | 0.88 | HTT (0.38) | HTTTRPA1 | |
| SCHEMBL8105080 | 0.88 | HTT (0.38) | HTTTRPA1 | |
| SCHEMBL9448189 | 0.82 | HTT (0.34) | HTT | |
| SCHEMBL9448155 | 0.82 | CTRB1 (0.31) | HTT | |
| SCHEMBL8423473 | 0.77 | HTT (0.37) | HTTLGALS8TRPA1 | |
| SCHEMBL9093078 | 0.77 | HTT (0.36) | HTTTRPA1 | |
| SCHEMBL7642568 | 0.77 | HTT (0.36) | HTTTRPA1 | |
| SCHEMBL7639470 | 0.77 | HTT (0.36) | HTTTRPA1 | |
| SCHEMBL7639804 | 0.77 | HTT (0.36) | HTTTRPA1 | |
| SCHEMBL9094926 | 0.76 | LGALS8 (0.39) | LGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532668-A1 | NOVEL -g(a)-GLUCOSIDASE INHIBITORS. | MERRELL DOW PHARMA (US) | 1993-03-24 | — | — | EP | disclosed |
| WO-1991018915-A1 | NOVEL α-GLUCOSIDASE INHIBITORS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-12-12 | — | — | WO | disclosed |