Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2176311 | 0.90 | GAA (0.45) | STAT3GAAGBA1ALDH1A1CYP3A4 | |
| SCHEMBL6431507 | 0.85 | CA2 (0.41) | STAT3GAAGBA1ALDH1A1CYP3A4 | |
| SCHEMBL4202226 | 0.85 | CA2 (0.41) | STAT3GAAGBA1ALDH1A1CYP3A4 | |
| SCHEMBL4202231 | 0.85 | CA2 (0.41) | STAT3GAAGBA1ALDH1A1CYP3A4 | |
| SCHEMBL4383356 | 0.83 | CA2 (0.43) | STAT3GAAGBA1ALDH1A1CYP3A4 | |
| SCHEMBL13104829 | 0.83 | STAT3 (0.43) | STAT3GAAGBA1ALDH1A1CYP3A4 | |
| SCHEMBL4383361 | 0.83 | CA2 (0.43) | STAT3GAAGBA1ALDH1A1CYP3A4 | |
| SCHEMBL9756838 | 0.83 | STAT3 (0.43) | STAT3GAAGBA1ALDH1A1CYP3A4 | |
| SCHEMBL9756774 | 0.83 | STAT3 (0.43) | STAT3GAAGBA1ALDH1A1CYP3A4 | |
| SCHEMBL15607874 | 0.83 | GBA1 (0.41) | STAT3GAAGBA1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124354-A | TREATMENT OF URINARY INCONTINENCE OR IRRITABLE BOWEL SYNDROME | PHARMACIA & UPJOHN AB (SE) | 2000-09-26 | — | — | US | disclosed |