Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1015907 | 0.88 | LMNA (0.35) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL4686877 | 0.88 | TP53 (0.30) | — | |
| SCHEMBL28592838 | 0.88 | BLM (0.41) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL28586829 | 0.86 | APP (0.41) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL8734767 | 0.86 | APP (0.41) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL8733536 | 0.86 | APP (0.41) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL28914373 | 0.85 | LMNA (0.39) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL3181159 | 0.84 | APP (0.39) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL28317422 | 0.83 | TP53 (0.32) | — | |
| SCHEMBL9403043 | 0.81 | TP53 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048390-A | DYE HAVING AT LEAST ONE CARBOXYL GROUP IN THE FORM OF A FREE ACID; A SECONDARY OR TERTIARY AMINE; ALKALI METAL HYDROXIDE | FUJI XEROX CO., LTD. (JP) | 2000-04-11 | — | — | US | disclosed |