SCHEMBL1015907

SCHEMBL1015907

NCCC(CCO)S(=O)(=O)O

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
SLC6A6 P31641 1/20 0.35
CYP2C19 P33261 1/20 0.35
BLM P54132 1/20 0.35
APP P05067 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
TP53 P04637 1/20 0.30
GABRR1 P24046 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28592838 0.90 BLM (0.41) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL8105490 0.88 APP (0.36) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL28914373 0.87 LMNA (0.39) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL270921 0.87 THRB (0.32) TP53
SCHEMBL3181159 0.86 APP (0.39) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL6838776 0.85 THRB (0.30) TP53
SCHEMBL4120188 0.83 LMNA (0.36) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL2231969 0.83 TP53 (0.31) LMNASLC6A6CYP2C19BLMTP53
SCHEMBL503109 0.83 TP53 (0.31) LMNASLC6A6CYP2C19BLMTP53
SCHEMBL27844573 0.81 TP53 (0.30) TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7816527-B2 Quinazoline-containing kits for labeling aldehyde or ketone moieties Life Technologies Corporation (US) 2010-10-19 US claimed
CN-101668854-A Compositions, systems, and methods for preserving and/or stabilizing cells and/or macromolecules SIERRA MOLECULAR CORP 2010-03-10 CN claimed
EP-1874955-A4 METHODS FOR PERFORMING DIRECT ENZYMATIC REACTIONS INVOLVING NUCLEIC ACID MOLECULES BIOQUEST INC (KR) 2009-05-06 EP claimed
US-7370952-B2 Ink, and, inkjet recording process, ink cartridge, recording unit, and inkjet recording apparatus using the ink RICOH COMPANY, LTD. (JP) 2008-05-13 US claimed
US-7368007-B2 Ink-jet recording ink, image forming method, ink-jet recording apparatus and imaged article RICOH COMPANY, LTD. (JP) 2008-05-06 US claimed
EP-1874955-A1 METHODS FOR PERFORMING DIRECT ENZYMATIC REACTIONS INVOLVING NUCLEIC ACID MOLECULES Bioquest, Inc. (KR) 2008-01-09 EP claimed
WO-2006090987-A1 METHODS FOR PERFORMING DIRECT ENZYMATIC REACTIONS INVOLVING NUCLEIC ACID MOLECULES BIOQUEST, INC. (KR) 2006-08-31 WO claimed
US-5704949-A SHELF STABLE HAIR DYES WITH MELANIN PRECURSORS AND REACTION OF DOPA THEN REARRANGEMENTS CLAIROL INCORPORATED (US) 1998-01-06 US claimed
US-20240139298-A1 MHC CLASS II T-CELL MODULATORY POLYPEPTIDES AND METHODS OF USE THEREOF CUE BIOPHARMA, INC. 2024-05-02 US disclosed
CN-117881413-A Granzyme activatable membrane interaction peptides and methods of use 加利福尼亚大学董事会 2024-04-12 CN disclosed
US-20220227833-A1 CD80 VARIANT PROTEINS AND USES THEREOF Xuanzhu Biopharmaceutical Co., Ltd. (CN) 2022-07-21 US disclosed
US-11377478-B2 T-cell modulatory multimeric polypeptides and methods of use thereof CUE BIOPHARMA, INC. (US) 2022-07-05 US disclosed
EP-3959225-A1 CD80 VARIANT PROTEINS AND USES THEREOF Xuanzhu Biopharmaceutical Co., Ltd. (CN) 2022-03-02 EP disclosed
EP-3943939-A1 MODIFICATION-DEPENDENT ACTIVITY ASSAYS Takeda Pharmaceutical Company Limited (JP) 2022-01-26 EP disclosed
EP-0969098-A1 HIGHLY SENSITIVE METHOD FOR ASSAYING CHIRO-INOSITOL AND COMPOSITIONS FOR THE ASSAY Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-01-05 EP disclosed
US-5827718-A DETERGENT STABILITY; BLENDS WITH PROTEASE; LAUNDRY DETERGENTS NOVO NORDISK A/S (DK) 1998-10-27 US disclosed
EP-0871854-A2 MEDIUM FOR DETECTING ENTEROCOCCI IN A SAMPLE IDEXX LABORATORIES, INC. (US) 1998-10-21 EP disclosed
WO-1998033530-A1 METHOD FOR DETECTING ABNORMAL EPITHELIAL CELL SHEDDING PHANOS TECHNOLOGIES, INC. (US) 1998-08-06 WO disclosed
WO-1996015435-A2 MEDIUM FOR DETECTING ENTEROCOCCI IN A SAMPLE IDEXX LABORATORIES, INC. (US) 1996-05-23 WO disclosed
US-5338671-A Reduce formation of non-specific products in polymerase chain reactions EASTMAN KODAK COMPANY (US) 1994-08-16 US disclosed