Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | PEPD | P12955 | 1/20 | 0.40 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29201779 | 0.80 | ALDH1A1 (0.51) | ALDH1A1NPC1GLAEPHX2ITGB1 | |
| SCHEMBL5557567 | 0.79 | MEN1 (0.43) | ALDH1A1NPC1EPHX2PEPDXPNPEP1 | |
| SCHEMBL15535092 | 0.78 | DPP4 (0.51) | ALDH1A1NPC1GLAEPHX2ITGB1 | |
| SCHEMBL15149731 | 0.78 | DPP4 (0.51) | ALDH1A1NPC1GLAEPHX2ITGB1 | |
| SCHEMBL1628767 | 0.78 | ALDH1A1 (0.50) | ALDH1A1NPC1GLAEPHX2ITGB1 | |
| SCHEMBL5671926 | 0.75 | ALDH1A1 (0.47) | ALDH1A1EPHX2MEN1KMT2A | |
| SCHEMBL4424458 | 0.74 | ALDH1A1 (0.54) | ALDH1A1NPC1EPHX2ITGB1ITGA4 | |
| SCHEMBL888273 | 0.74 | ALDH1A1 (0.50) | ALDH1A1NPC1EPHX2ITGB1ITGA4 | |
| SCHEMBL7978294 | 0.74 | LMNA (0.44) | ALDH1A1EPHX2MEN1KMT2A | |
| SCHEMBL3292905 | 0.74 | ALDH1A1 (0.42) | ALDH1A1NPC1EPHX2ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133957-A1 | IMMOBILIZED ENZYME AND USE THEREOF IN CONTINUOUS PRODUCTION | 凯莱英生命科学技术(天津)有限公司 | 2023-07-20 | — | — | WO | disclosed |
| US-8809024-B2 | Process for preparing dipeptidyl peptidase IV inhibitors and intermediates therefor | ASTRAZENECA AB (SE) | 2014-08-19 | — | — | US | disclosed |
| US-8809024-B2 | Process for preparing dipeptidyl peptidase IV inhibitors and intermediates therefor | ASTRAZENECA AB (SE) | 2014-08-19 | — | — | US | disclosed |
| US-20130204012-A1 | Process For Preparing Dipeptidyl Peptidase IV Inhibitors And Intermediates Therefor | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-08-08 | — | — | US | disclosed |
| US-20130204012-A1 | Process For Preparing Dipeptidyl Peptidase IV Inhibitors And Intermediates Therefor | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-08-08 | — | — | US | disclosed |
| US-8361761-B2 | Process for preparing dipeptidyl peptidase IV inhibitors and intermediates therefor | BRISTOL MYERS-SQUIBB COMPANY (US) | 2013-01-29 | — | — | US | disclosed |
| US-8361761-B2 | Process for preparing dipeptidyl peptidase IV inhibitors and intermediates therefor | BRISTOL MYERS-SQUIBB COMPANY (US) | 2013-01-29 | — | — | US | disclosed |
| US-20130012723-A1 | METHODS AND COMPOUNDS FOR PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-01-10 | — | — | US | disclosed |
| US-20130012723-A1 | METHODS AND COMPOUNDS FOR PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-01-10 | — | — | US | disclosed |
| US-20120276600-A1 | Process For Preparing Dipeptidyl Peptidase IV Inhibitors And Intermediates Therefor | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-11-01 | — | — | US | disclosed |
| US-7705033-B2 | Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-04-27 | — | — | US | disclosed |
| US-20090018311-A1 | METHODS AND COMPOUNDS FOR PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-01-15 | — | — | US | disclosed |
| US-20090018311-A1 | METHODS AND COMPOUNDS FOR PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-01-15 | — | — | US | disclosed |
| US-7420079-B2 | Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-09-02 | — | — | US | disclosed |
| US-7420079-B2 | Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-09-02 | — | — | US | disclosed |
| US-7205432-B2 | Process for the preparation of adamantane derivatives | KEMFINE OY (FI) | 2007-04-17 | — | — | US | disclosed |
| US-7205432-B2 | Process for the preparation of adamantane derivatives | KEMFINE OY (FI) | 2007-04-17 | — | — | US | disclosed |
| EP-0661271-B1 | AZEPINE DERIVATIVES, PRODUCTION THEREOF, AND USE THEREOF AS SIGMA-RECEPTOR LIGANDS | ASAHI CHEMICAL IND (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5658923-A | USED IN TREATING DISEASES RELATED TO SIGMA-RECEPTOR, SUCH AS SCHIZOPHRENIA | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0661271-A1 | AZEPINE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1995-07-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018311-A1 | METHODS AND COMPOUNDS FOR PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF | DPP4, DPP3, DPP8 | ALDH1A1 1007/4885NPC1 884/4885GLA 1373/4885 |
| US-20120276600-A1 | Process For Preparing Dipeptidyl Peptidase IV Inhibitors And Intermediates Therefor | DNPEP, DPP4, DPP8 | ALDH1A1 403/4885NPC1 2261/4885GLA 3496/4885 |
| US-20130012723-A1 | METHODS AND COMPOUNDS FOR PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF | DPP4, DPP3, DPP8 | ALDH1A1 1007/4885NPC1 884/4885GLA 1373/4885 |
| US-20130204012-A1 | Process For Preparing Dipeptidyl Peptidase IV Inhibitors And Intermediates Therefor | DNPEP, DPP4, PEPD | ALDH1A1 377/4885NPC1 2284/4885GLA 3582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.