SCHEMBL29201779

SCHEMBL29201779

COC(=O)C(C)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.51
NPC1 O15118 1/20 0.50
EPHX2 P34913 5/20 0.44
SLC22A2 O15244 1/20 0.43
SLC47A1 Q96FL8 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
MAPT P10636 1/20 0.42
GLA P06280 1/20 0.42
DPP4 P27487 1/20 0.41
ITGB1 P05556 1/20 0.40
ITGA4 P13612 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25285769 0.92 ALDH1A1 (0.42) ALDH1A1NPC1EPHX2MEN1KMT2A
SCHEMBL8105673 0.80 ALDH1A1 (0.51) ALDH1A1NPC1EPHX2SLC22A2SLC47A1
SCHEMBL15149731 0.78 DPP4 (0.51) ALDH1A1NPC1EPHX2SLC22A2SLC47A1
SCHEMBL15535092 0.78 DPP4 (0.51) ALDH1A1NPC1EPHX2SLC22A2SLC47A1
SCHEMBL1628767 0.78 ALDH1A1 (0.50) ALDH1A1NPC1EPHX2SLC22A2SLC47A1
SCHEMBL15149727 0.77 ALDH1A1 (0.50) ALDH1A1NPC1EPHX2SLC22A2SLC47A1
SCHEMBL1089252 0.77 ALDH1A1 (0.50) ALDH1A1NPC1EPHX2SLC22A2SLC47A1
SCHEMBL8073575 0.77 ALDH1A1 (0.50) ALDH1A1NPC1EPHX2SLC22A2SLC47A1
SCHEMBL4138799 0.77 NPC1 (0.50) ALDH1A1NPC1EPHX2SLC22A2SLC47A1
SCHEMBL26849833 0.77 DPP4 (0.41) ALDH1A1NPC1DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117447466-A Oxazole compound and preparation method and application thereof 中国科学院上海药物研究所 2024-01-26 CN disclosed