Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670970 | 0.72 | FNTA (0.44) | KDM4EFNTAFNTB | |
| SCHEMBL4670972 | 0.72 | FNTA (0.44) | KDM4EFNTAFNTB | |
| SCHEMBL8105746 | 0.70 | HDAC3 (0.49) | KDM4EMAPT | |
| SCHEMBL8105854 | 0.64 | FNTA (0.44) | MAPTKMT2AFNTAFNTB | |
| SCHEMBL5371376 | 0.63 | ABCG2 (0.59) | ABCB1ABCG2RAB9ANPC1POLB | |
| SCHEMBL18689299 | 0.63 | ABCG2 (1.00) | ABCB1ABCG2RAB9ANPC1KDM4E | |
| SCHEMBL14925414 | 0.63 | RAB9A (0.54) | ABCB1ABCG2RAB9ANPC1KDM4E | |
| SCHEMBL3887692 | 0.62 | POLB (0.56) | ABCB1ABCG2POLBMAPTNPSR1 | |
| SCHEMBL18689326 | 0.62 | ABCB1 (0.76) | ABCB1ABCG2RAB9ANPC1KDM4E | |
| SCHEMBL11116897 | 0.62 | ABCG2 (0.57) | ABCB1ABCG2RAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143744-A | Sulfamide-metalloprotease inhibitors | SYNTEX (U.S.A.) INC. (US) | 2000-11-07 | — | — | US | disclosed |
| US-5998412-A | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | SYNTEX (U.S.A.) INC. (US) | 1999-12-07 | — | — | US | disclosed |