Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.44 |
| ▸ | FNTB | P49356 | 3/20 | 0.44 |
| ▸ | NMBR | P28336 | 7/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTPRA | P18433 | 1/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670970 | 0.78 | FNTA (0.44) | FNTAFNTBKDR | |
| SCHEMBL4670972 | 0.78 | FNTA (0.44) | FNTAFNTBKDR | |
| SCHEMBL8105859 | 0.64 | ABCB1 (0.45) | FNTAFNTBMAPTKMT2A | |
| SCHEMBL1065198 | 0.64 | PTPRA (0.53) | FNTAFNTBMAPTPTPRAKMT2A | |
| SCHEMBL6573455 | 0.62 | PTPRA (0.50) | FNTAFNTBMAPTPTPRAKMT2A | |
| SCHEMBL6668651 | 0.61 | FNTA (1.00) | FNTAFNTB | |
| SCHEMBL6668444 | 0.60 | FNTA (1.00) | FNTAFNTB | |
| SCHEMBL8105746 | 0.60 | HDAC3 (0.49) | LMNAMAPT | |
| SCHEMBL10127528 | 0.60 | KMT2A (0.51) | LMNAMAPTKMT2A | |
| SCHEMBL15016414 | 0.59 | L3MBTL1 (0.46) | FNTAFNTBLMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143744-A | Sulfamide-metalloprotease inhibitors | SYNTEX (U.S.A.) INC. (US) | 2000-11-07 | — | — | US | disclosed |
| US-6130220-A | ENZYME INHIBITORS | SYNTEX (USA) INC. (US) | 2000-10-10 | — | — | US | disclosed |
| US-5998412-A | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | SYNTEX (U.S.A.) INC. (US) | 1999-12-07 | — | — | US | disclosed |