Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 4/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | CASP7 | P55210 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8071735 | 0.76 | CASP1 (0.38) | CASP1PDE10AALDH1A1PLA2G7KDM4E | |
| SCHEMBL8100528 | 0.74 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL8091145 | 0.74 | S100B (0.35) | POLBGAANPC1RAB9AMEN1 | |
| SCHEMBL7807676 | 0.69 | CASP1 (0.42) | CASP1PDE10AALDH1A1PLA2G7KDM4E | |
| SCHEMBL3338155 | 0.68 | CASP1 (0.46) | CASP1PDE10AALDH1A1POLBACHE | |
| SCHEMBL7461860 | 0.68 | CASP1 (0.40) | CASP1PDE10AALDH1A1POLBPLA2G7 | |
| SCHEMBL6572515 | 0.68 | POLB (0.68) | CASP1PDE10AALDH1A1POLBPLA2G7 | |
| SCHEMBL7805986 | 0.67 | CASP1 (0.39) | CASP1PDE10AALDH1A1PLA2G7KDM4E | |
| SCHEMBL6571968 | 0.66 | CASP1 (0.52) | CASP1PDE10AALDH1A1POLBPLA2G7 | |
| SCHEMBL2479814 | 0.65 | TDP1 (0.50) | CASP1ALDH1A1POLBKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6042620-A | FOR DYEING KERATIN FIBERS SUCH AS HAIR | WELLA AG (DE) | 2000-03-28 | — | — | US | disclosed |