Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 4/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27544391 | 1.00 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL7272751 | 0.88 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL7265100 | 0.88 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL8787182 | 0.85 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL8787113 | 0.84 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL8787955 | 0.79 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL7301260 | 0.74 | MME (0.44) | ALDH1A1L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL23578402 | 0.74 | BACE1 (0.48) | ALDH1A1L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL23578399 | 0.74 | BACE1 (0.48) | ALDH1A1L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL9391159 | 0.74 | EPHX1 (0.55) | KMT2AELANEEPHX1HPGDSPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1495186-A | Method for preparing enkephalinase and angiotensin-converting enzyme inhibitor intermediate and its intermediate | ���µ�˹ҩ�﹫˾ | 2004-05-12 | — | — | CN | disclosed |
| CN-1113894-C | Process for preparing intermediates of inhibitors of enkephalinase and angiotensin converting enzyme and intermediates thereof | AVENTIS PHARMA INC (US) | 2003-07-09 | — | — | CN | disclosed |
| EP-0800527-B1 | NOVEL PROCESSES FOR PREPARING INTERMEDIATES OF INHIBITORS OF ENKEPHALINASE AND ANGIOTENSIN CONVERTING ENZYME AND INTERMEDIATES THEREOF | HOECHST MARION ROUSSEL INC (US) | 2000-03-08 | — | — | EP | disclosed |
| EP-0957109-A2 | Novel processes for preparing intermediates of inhibitors of enkephalinase and angiotensin converting enzyme and intermediates thereof | HOECHST MARION ROUSSEL, INC. (US) | 1999-11-17 | — | — | EP | disclosed |
| US-5872251-A | Process for preparing intermediates of inhibitors of enkephalinase and angiotensin converting enzyme and intermediates thereof | HOECHST MARION ROUSSEL, INC. (US) | 1999-02-16 | — | — | US | disclosed |
| US-5859252-A | Processes for preparing intermediates of inhibitors of enkephalinase and angiotensin converting enzyme and intermediates thereof | HOECHST MARION ROUSSEL, INC. (US) | 1999-01-12 | — | — | US | disclosed |
| US-5849908-A | Processes for preparing intermediates of inhibitors of enkephalinase and angiotensin converting enzyme and intermediates thereof | HOECHST MARION ROUSSEL INC. (US) | 1998-12-15 | — | — | US | disclosed |
| US-5734049-A | Processes for preparing intermediates of inhibitors of enkephalinase and angiotensin converting enzyme and intermediates thereof | HOECHST MARION ROUSSEL, INC. (US) | 1998-03-31 | — | — | US | disclosed |
| CN-1170413-A | Process for preparing intermediates of inhibitors of enkephalinase and angiotensin converting enzyme and intermediates thereof | HOECHEST MARION ROUSSEL INC (US) | 1998-01-14 | — | — | CN | disclosed |
| EP-0800527-A1 | NOVEL PROCESSES FOR PREPARING INTERMEDIATES OF INHIBITORS OF ENKEPHALINASE AND ANGIOTENSIN CONVERTING ENZYME AND INTERMEDIATES THEREOF | HOECHST MARION ROUSSEL, INC. (US) | 1997-10-15 | — | — | EP | disclosed |
| US-5641880-A | Processes for preparing intermediates of inhibitors of enkephalinase and angiotensin converting enzyme and intermediates thereof | HOECHST MARION ROUSSEL, INC. (US) | 1997-06-24 | — | — | US | disclosed |
| WO-1996019492-A1 | NOVEL PROCESSES FOR PREPARING INTERMEDIATES OF INHIBITORS OF ENKEPHALINASE AND ANGIOTENSIN CONVERTING ENZYME AND INTERMEDIATES THEREOF | HOECHST MARION ROUSSEL, INC. (US) | 1996-06-27 | — | — | WO | disclosed |