Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 12/20 | 0.64 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8106090 | 0.97 | GPR35 (0.62) | GPR35CYSLTR2CYSLTR1GPR55NPC1 | |
| SCHEMBL7897848 | 0.87 | GPR35 (0.59) | GPR35CYSLTR2CYSLTR1GPR55ADORA1 | |
| SCHEMBL7896347 | 0.87 | GPR35 (0.59) | GPR35CYSLTR2CYSLTR1GPR55ADORA1 | |
| SCHEMBL8122225 | 0.87 | GPR35 (0.62) | GPR35CYSLTR2CYSLTR1GPR55NPC1 | |
| SCHEMBL7897075 | 0.86 | GPR35 (0.62) | GPR35CYSLTR2CYSLTR1GPR55NPC1 | |
| SCHEMBL8107932 | 0.84 | GPR35 (0.59) | GPR35CYSLTR2CYSLTR1NPC1RAB9A | |
| SCHEMBL8109312 | 0.84 | GPR35 (0.61) | GPR35CYSLTR2CYSLTR1GPR55ADORA1 | |
| SCHEMBL6956919 | 0.83 | GPR35 (0.57) | GPR35CYSLTR2CYSLTR1GPR55ADORA1 | |
| SCHEMBL6951132 | 0.83 | GPR35 (0.57) | GPR35CYSLTR2CYSLTR1GPR55ADORA1 | |
| SCHEMBL6958010 | 0.82 | GPR35 (0.60) | GPR35CYSLTR2CYSLTR1GPR55NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634409-B1 | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL CO (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5659051-A | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0634409-A1 | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-01-18 | — | — | EP | disclosed |