Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 10/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8122842 | 0.97 | GPR35 (0.58) | GPR35L3MBTL1MEN1KMT2ACYSLTR2 | |
| SCHEMBL8122225 | 0.91 | GPR35 (0.62) | GPR35L3MBTL1MEN1KMT2ACYSLTR2 | |
| SCHEMBL8109312 | 0.88 | GPR35 (0.61) | GPR35L3MBTL1MEN1KMT2ACYSLTR2 | |
| SCHEMBL8106887 | 0.84 | GPR35 (0.64) | GPR35MEN1KMT2ACYSLTR2CYSLTR1 | |
| SCHEMBL8107145 | 0.82 | GPR35 (0.70) | GPR35CYSLTR2CYSLTR1 | |
| SCHEMBL4254475 | 0.82 | GPR35 (0.69) | GPR35CYSLTR2CYSLTR1 | |
| SCHEMBL8106090 | 0.81 | GPR35 (0.62) | GPR35CYSLTR2CYSLTR1RAB9ANPC1 | |
| SCHEMBL8106151 | 0.81 | MAOB (0.54) | L3MBTL1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL7896347 | 0.79 | GPR35 (0.59) | GPR35CYSLTR2CYSLTR1 | |
| SCHEMBL7897848 | 0.79 | GPR35 (0.59) | GPR35CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634409-B1 | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL CO (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5659051-A | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0634409-A1 | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-01-18 | — | — | EP | disclosed |