Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 11/20 | 0.61 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.51 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8122225 | 0.97 | GPR35 (0.62) | GPR35CYSLTR2CYSLTR1KDM4EMEN1 | |
| SCHEMBL8122842 | 0.91 | GPR35 (0.58) | GPR35CYSLTR2CYSLTR1MEN1KMT2A | |
| SCHEMBL8107932 | 0.88 | GPR35 (0.59) | GPR35CYSLTR2CYSLTR1MEN1KMT2A | |
| SCHEMBL8106090 | 0.87 | GPR35 (0.62) | GPR35CYSLTR2CYSLTR1POLBGPR55 | |
| SCHEMBL7896347 | 0.84 | GPR35 (0.59) | GPR35CYSLTR2CYSLTR1GPR55ABCC4 | |
| SCHEMBL7897848 | 0.84 | GPR35 (0.59) | GPR35CYSLTR2CYSLTR1GPR55ABCC4 | |
| SCHEMBL8106887 | 0.84 | GPR35 (0.64) | GPR35CYSLTR2CYSLTR1MEN1KMT2A | |
| SCHEMBL6956919 | 0.83 | GPR35 (0.57) | GPR35CYSLTR2CYSLTR1GPR55ABCC4 | |
| SCHEMBL6951132 | 0.83 | GPR35 (0.57) | GPR35CYSLTR2CYSLTR1GPR55ABCC4 | |
| SCHEMBL4255927 | 0.82 | GPR35 (0.69) | GPR35CYSLTR2CYSLTR1GPR55ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719775-B1 | Substituted 4-phenyl thiazole derivatives, process for their preparation and pharmaceutical compositions containing them | SANOFI SYNTHELABO (FR) | 2000-07-12 | — | — | EP | disclosed |
| EP-0634409-B1 | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL CO (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5659051-A | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0719775-A1 | Substituted 4-phenyl thiazole derivatives, process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1996-07-03 | — | — | EP | disclosed |
| EP-0634409-A1 | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-01-18 | — | — | EP | disclosed |