Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209897 | 0.90 | KMT2A (0.36) | KMT2AHSP90AA1HSP90AB1SMN1; SMN2KDM4E | |
| SCHEMBL8112940 | 0.88 | KMT2A (0.35) | KMT2AHSP90AA1HSP90AB1SMN1; SMN2KDM4E | |
| SCHEMBL19261230 | 0.88 | KMT2A (0.35) | KMT2AHSP90AA1HSP90AB1SMN1; SMN2KDM4E | |
| SCHEMBL8111418 | 0.86 | KMT2A (0.33) | KMT2AHSP90AA1HSP90AB1SMN1; SMN2KDM4E | |
| SCHEMBL8097626 | 0.85 | FGFR1 (0.33) | KMT2AHSP90AA1HSP90AB1SMN1; SMN2KDM4E | |
| SCHEMBL8106875 | 0.85 | OPRM1 (0.34) | KMT2AHSP90AA1HSP90AB1SMN1; SMN2KDM4E | |
| SCHEMBL7209825 | 0.85 | PDK1 (0.40) | KMT2AHSP90AA1HSP90AB1KDM4EHPGD | |
| SCHEMBL8105338 | 0.84 | HPGD (0.35) | KMT2ASMN1; SMN2KDM4EHPGDALDH1A1 | |
| SCHEMBL8097651 | 0.84 | LMNA (0.34) | KMT2ASMN1; SMN2KDM4EHPGDALDH2 | |
| SCHEMBL8097596 | 0.84 | ADORA1 (0.35) | KMT2ASMN1; SMN2KDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6046135-A | FOR CONTROLLING WEEDS | RHONE-POULENC AGRICULTURE LTD (GB) | 2000-04-04 | — | — | US | claimed |
| US-6046135-A | FOR CONTROLLING WEEDS | RHONE-POULENC AGRICULTURE LTD (GB) | 2000-04-04 | — | — | US | disclosed |