Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097877 | 0.84 | HTT (0.47) | HTTMAPTLMNAKMT2AMEN1 | |
| SCHEMBL8104222 | 0.78 | AXL (0.34) | HTTSMN1; SMN2AXL | |
| SCHEMBL8103652 | 0.77 | SMN1; SMN2 (0.34) | SMN1; SMN2 | |
| SCHEMBL8595657 | 0.77 | HTT (0.41) | HTTMAPTLMNAKMT2AMEN1 | |
| SCHEMBL8484934 | 0.76 | MYC (0.56) | LMNAKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8099674 | 0.76 | SMN1; SMN2 (0.35) | SMN1; SMN2 | |
| SCHEMBL8090469 | 0.75 | SMN1; SMN2 (0.34) | SMN1; SMN2 | |
| SCHEMBL29167150 | 0.74 | AXL (0.68) | HTTMAPTLMNAKMT2AMEN1 | |
| SCHEMBL8100274 | 0.72 | ALDH1A1 (0.34) | LMNAKMT2AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13735702 | 0.70 | LMNA (0.50) | HTTMAPTLMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096895-A | Heterocyclic dihydrazole compounds and their use for controlling fungal plant diseases | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-08-01 | — | — | US | disclosed |