Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | CCR9 | P51686 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8595657 | 0.91 | HTT (0.41) | HTTMAPTLMNAKMT2AMEN1 | |
| SCHEMBL8106915 | 0.84 | HTT (0.50) | HTTMAPTLMNAKMT2AMEN1 | |
| SCHEMBL8481561 | 0.76 | MYC (0.56) | LMNAKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL29167150 | 0.74 | AXL (0.68) | HTTMAPTLMNAKMT2AMEN1 | |
| SCHEMBL8104540 | 0.72 | ALDH1A1 (0.33) | HTTMAPTLMNAKMT2AMEN1 | |
| SCHEMBL13735702 | 0.70 | LMNA (0.50) | HTTMAPTLMNAKMT2AMEN1 | |
| SCHEMBL159806 | 0.68 | KMT2A (0.56) | HTTMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL8875381 | 0.68 | MAPT (0.58) | HTTMAPTLMNAKMT2AMEN1 | |
| SCHEMBL8480846 | 0.68 | ALDH1A1 (0.41) | HTTMAPTLMNAALDH1A1POLB | |
| SCHEMBL28433006 | 0.67 | HTT (0.54) | HTTMAPTLMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096895-A | Heterocyclic dihydrazole compounds and their use for controlling fungal plant diseases | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-08-01 | — | — | US | disclosed |