Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | HPGD | P15428 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17510042 | 0.77 | PARP1 (0.48) | ALDH1A1HPGDKDM4EHSD17B10MEN1 | |
| SCHEMBL14349887 | 0.74 | PDE9A (0.52) | PARP1 | |
| SCHEMBL10572503 | 0.74 | KDM4E (0.57) | ALDH1A1HPGDKDM4EHSD17B10MEN1 | |
| SCHEMBL6050482 | 0.72 | ALDH1A1 (0.55) | ALDH1A1HPGDKDM4EHSD17B10MEN1 | |
| SCHEMBL29394356 | 0.72 | ALDH1A1 (0.55) | ALDH1A1HPGDKDM4EHSD17B10MEN1 | |
| SCHEMBL5307307 | 0.72 | KDM4E (1.00) | RAB9AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL15338397 | 0.71 | RAB9A (0.77) | RAB9AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL29722594 | 0.71 | RAB9A (0.77) | RAB9AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL28274604 | 0.69 | HTR2A (0.51) | ALDH1A1HPGD | |
| SCHEMBL19297202 | 0.68 | HTR6 (0.49) | ALDH1A1HPGDKDM4EHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121286-A | ANTILEUKOTRIENE ACTIVITY AND ANTIHISTAMINIC ACTIVITY, FOR TREATING ASTHMA; COMPOUNDS SUCH AS 6-METHOXY-3-(2-(3-(2-QUINOLYLMETHOXY)BENZYL)TETRAZOLYL)QUINOLIN-2-ONE | KOWA CO., LTD. (JP) | 2000-09-19 | — | — | US | disclosed |
| US-6117886-A | EXCELLENT ANTILEUKOTRIENE ACTIVITY AND ANTIHISTAMINIC ACTIVITY, AND IS USEFUL FOR THE PREVENTION AND TREATMENT OF, FOR EXAMPLE, ASTHMA. | KOWA CO., LTD. (JP) | 2000-09-12 | — | — | US | disclosed |