Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | VDR | P11473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13317672 | 0.79 | CDC25A (0.42) | CDC25ACDC25B | |
| SCHEMBL13298446 | 0.72 | CYP19A1 (0.39) | VDR | |
| SCHEMBL7145450 | 0.67 | CDC25A (0.38) | CDC25ACDC25B | |
| SCHEMBL8229897 | 0.67 | CDC25A (0.38) | CDC25ACDC25B | |
| SCHEMBL8107009 | 0.67 | CDC25A (0.38) | CDC25ACDC25B | |
| SCHEMBL27461585 | 0.67 | CDC25A (0.38) | CDC25ACDC25B | |
| SCHEMBL9718353 | 0.67 | CDC25A (0.56) | CDC25ACDC25B | |
| SCHEMBL9679574 | 0.67 | CDC25A (0.56) | CDC25ACDC25B | |
| SCHEMBL14294634 | 0.66 | CDC25A (0.38) | CDC25ACDC25B | |
| SCHEMBL6694809 | 0.66 | CDC25A (0.38) | CDC25ACDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170114013-A1 | LOW CALCEMIC, HIGHLY ANTIPROLIFERATIVE, ANALOGS OF CALCITRIOL | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2017-04-27 | — | — | US | disclosed |
| US-20170114013-A1 | LOW CALCEMIC, HIGHLY ANTIPROLIFERATIVE, ANALOGS OF CALCITRIOL | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2017-04-27 | — | — | US | disclosed |
| US-9481646-B2 | Low calcemic, highly antiproliferative, analogs of calcitriol | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-11-01 | — | — | US | disclosed |
| US-9481646-B2 | Low calcemic, highly antiproliferative, analogs of calcitriol | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-11-01 | — | — | US | disclosed |
| US-20100137262-A1 | Low Calcemic, Highly Antiproliferative, Analogs of Calcitriol | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170114013-A1 | LOW CALCEMIC, HIGHLY ANTIPROLIFERATIVE, ANALOGS OF CALCITRIOL | VDR, CYP24A1, CYP27B1 | CDC25A 85/4885CDC25B 147/4885VDR 1/4885 |
| US-20100137262-A1 | Low Calcemic, Highly Antiproliferative, Analogs of Calcitriol | VDR, CYP24A1, CYP27B1 | CDC25A 85/4885CDC25B 147/4885VDR 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.