Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 10/20 | 0.70 |
| ▸ | CYSLTR2 | Q9NS75 | 9/20 | 0.64 |
| ▸ | CYSLTR1 | Q9Y271 | 9/20 | 0.64 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | PGR | P06401 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | AR | P10275 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | DRD1 | P21728 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | PDE4A | P27815 | 1/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.61 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4254475 | 0.97 | GPR35 (0.69) | GPR35CYSLTR2CYSLTR1ABCC4ABCB11 | |
| SCHEMBL8108390 | 0.92 | GPR35 (0.70) | GPR35CYSLTR2CYSLTR1ABCC4ABCB11 | |
| SCHEMBL4255927 | 0.89 | GPR35 (0.69) | GPR35CYSLTR2CYSLTR1ABCC4ABCB11 | |
| SCHEMBL8121976 | 0.87 | GPR35 (0.69) | GPR35CYSLTR2CYSLTR1ABCC4ABCB11 | |
| SCHEMBL8106555 | 0.87 | GPR35 (0.66) | GPR35CYSLTR2CYSLTR1ABCC4ABCB11 | |
| SCHEMBL4250595 | 0.85 | CYSLTR2 (0.68) | GPR35CYSLTR2CYSLTR1ABCC4ABCB11 | |
| SCHEMBL6956132 | 0.84 | CYSLTR2 (0.67) | GPR35CYSLTR2CYSLTR1ABCC4ABCB11 | |
| SCHEMBL8121606 | 0.83 | POLB (0.54) | GPR35CYSLTR2CYSLTR1NR1H4 | |
| SCHEMBL6956128 | 0.83 | CYSLTR2 (0.66) | GPR35CYSLTR2CYSLTR1ABCC4ABCB11 | |
| SCHEMBL7889217 | 0.82 | CYSLTR2 (0.65) | GPR35CYSLTR2CYSLTR1ABCC4ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634409-B1 | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL CO (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5659051-A | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0634409-A1 | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-01-18 | — | — | EP | disclosed |